題目:Seeing life in a new light (以新的光學成像方式觀察生命)
報告人:Vladislav Yakovlev教授, 美國德州農工大學物理系(Texas A&M University)
時間:2019年5月13日,上午9:30
地點:光電大樓104室
摘要:
The progress of biomedical sciences depends on the availability of advanced instrumentation and imaging tools capable of attaining the state of biological systems in vivo without using exogenous markers. Mechanical forces and local elasticity play a central role in understanding physical interactions in all living systems. We demonstrate a novel way to image microscopic viscoelastic properties of biological systems using Brillouin microspectroscopy [1]. In my talk, I will discuss the ways how an old spectroscopic tool can be used for real time microscopic imaging and provide possible solutions to long standing problems in Life Sciences and Medicine [2-4].
[1] Zh. Meng, et al, “Seeing cells in a new light: a renaissance of Brillouin spectroscopy,” Advances in Optics and Photonics 8(2), 300-327 (2016).
[2] C. W. Ballmann, et al, “Impulsive Brillouin microscopy,” Optica 4(1), 124-128 (2017).
[3] Zh. Meng, et al, “Assessment of local heterogeneity in mechanical properties of a bulk hydrogel network,” ACS Nano 11(8), 7690–7696 (2017).
[4] M. Troyanova-Wood, et al, “Differentiating melanoma and healthy tissues based on elasticity-specific Brillouin microspectroscopy,” Biomedical Optics Express 10(4), 1774-1781 (2019).
報告人簡介:
ladislav V. Yakovlev博士是德州農工大學生物醫學工程、電子和計算工程和物理與天文學院的教授。1990年,他從莫斯科國立大學獲得博士學位。隨后,他在UCSD的化學和生物化學系擔任博士后研究員和研究人員,開發了光學分子光譜、成像和控制的新工具。Yakovlev博士于1998年在威斯康星大學密爾沃基分校擔任助理教授,并于2011年遷往德州農工大學(Texas A&M University)。他在主要的科學期刊上發表了150多篇研究論文。他的研究得到了NSF, NIH, ARO, AFOSR, ONR和DARPA的支持。Yakovlev博士是OSA, APS, SPIE, AIMBE的會士(fellow)。他目前擔任Optica, Journal of Biomedical Optics,Applied Sciences的編輯委員會成員。他的研究興趣廣泛分布在光譜學、顯微學、成像和傳感領域。







